在接受体外膜氧化治疗的患者中急性损伤:回顾性队列研究
Aswin Surjit1, Bipi Prasannan2, Jobin Abraham3
1Department of Internal Medicine, Aster Medcity, Kochi, Kerala, India.
概括
急性损伤 (AKI) 影响了超过一半的体外膜氧化 (ECMO) 患者. 早期AKI检测和管理至关重要,因为AKI独立地增加了这些重症患者的死亡风险.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 关键护理医学 关键护理医学
- 心脏病学 心脏病学
背景情况:
- 身体外膜氧化 (ECMO) 为严重的心脏或呼吸系统衰竭提供生命支持.
- 急性损伤 (AKI) 是一种已知的并发症,可以对患者的结果产生负面影响.
- 了解ECMO患者的AKI发生率和结果对于改善护理至关重要.
研究的目的:
- 为了确定接受ECMO的患者中AKI的发病率.
- 在ECMO期间识别与AKI发展相关的风险因素.
- 评估AKI对ECMO患者死亡率的影响.
主要方法:
- 64名接受ECMO治疗超过24小时的患者的回顾性队列研究.
- 排除在48小时内死亡或患有末期脏疾病的患者.
- 基于病改善全球结果 (KDIGO) 标准的AKI诊断和分期.
主要成果:
- 59.38%的患者患有AKI,其中44.73%的患者在ECMO启动后24小时内患有AKI.
- AKI的危险因素包括年龄,APACHE-II评分,高血压,毒药物,内支持和心脏功能不佳.
- 在AKI患者中,总死亡率为67.19%,明显高 (81.58%).
结论:
- AKI是ECMO患者常见和严重的并发症.
- AKI是该人口中死亡率的独立预测指标.
- 早期识别和管理AKI风险因素可能会提高生存率.
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