各种外科手术的预后影响和胃食道结点瘤的术后边缘状况
Mira Sudam Wagh1, Chandramohan K1, Abdulla Kp1
1Division of Surgical Oncology, Department of Surgical Services, Regional Cancer Centre, Thiruvananthapuram, Kerala India.
Indian journal of surgical oncology
|March 21, 2024
概括
在食管胃结 (EGJ) 癌症中,手术边缘显著影响存活率. 积极的边缘,特别是近端边缘,与较差的结果有关,这表明对这些癌症来说,仔细的手术规划至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 在瘤学瘤学.
背景情况:
- 胃食管结 (EGJ) 癌症经常需要广泛的手术方法.
- 对于所有EGJ癌症患者来说,进入胸腔和腹腔的必要性仍然是争论的主题.
- 手术边缘和淋巴切除术是影响患者结果的关键因素.
研究的目的:
- 分析手术边缘状态对EGJ癌症患者的生存结果的影响.
- 评估不同外科手术对极限阳性和生存率的影响.
- 评估EGJ腺癌的外科治疗后的长期存活数据.
主要方法:
- 一个前性维护的数据库的回顾性分析.
- 包括2014年1月至2016年12月间经过EGJ腺癌手术的94名患者.
- 评估边际状态 (近端,远端,辐射) 和存活率 (整体和无疾病),至少进行5年的随访.
主要成果:
- 8名 (8.51%) 患者患有近端边缘,其中2名患有远端边缘.
- 17名 (18.09%) 和5名 (5.32%) 患者分别有接近近端和远端边缘.
- 靠近胃切除术与较高的靠近边缘阳性相关;积极或接近的边缘对生存有负面影响.
结论:
- 在EGJ癌症中,积极的外科手术边缘与总体和无病生存率显著降低有关.
- 靠近胃切除术增加了靠近边缘阳性的风险.
- 需要进一步的前性研究来确定边缘参与是否是瘤侵略性的标志物或评估错误.
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