CircZCCHC2 (hsa_circ_0000854) 通过调节miR-936/BTBD7轴和激活Rho/ROCK2通路来促进肝细胞癌的进展

Junjie Yin1, Mian Wang2, Jian Chen1

  • 1Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, School of medicine, Westlake university, Hangzhou, 310006, China.

PubMed
概括

一种新型的循环RNA,circZCCHC2,在肝细胞癌 (HCC) 中被上调,促进癌症生长和转移. 这种circRNA向miR-936,影响BTBD7/Rho/ROCK2通路,并表明HCC患者的预后不佳.

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