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Updated: Jul 30, 2026

Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS
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Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS

Published on: November 8, 2015

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开发和验证一种LC-MSMS方法,以从干燥的血斑中量化肌

Carlos Torres1, Rogers A Muldrow1, Anissa R Naranjo1

  • 1LetsGetCheked, Monrovia, CA, USA.

Journal of mass spectrometry and advances in the clinical lab
|March 21, 2024
PubMed
概括

我们开发了一种精确的液体染色学-并联质谱法 (LC-MSMS) 试验,用于测量干血斑点 (DBS) 中的肌素. 这种方法改善了慢性病查的测试访问,并且至少在10天内保持稳定.

关键词:
慢性病查 慢性病查肌氨酸 (creatinine) 是一种蛋白质.干燥的血液斑点 干燥的血液斑点这是LC-MS/MS.

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High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry10:17

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In healthy individuals, serum creatinine levels remain stable due to a balance between its constant production—primarily from muscle metabolism—and renal excretion. Creatinine is freely filtered by the glomeruli, making it a valuable marker for estimating renal function. When the glomerular filtration rate (GFR) decreases, the kidneys can only eliminate less creatinine, causing serum levels to rise.Serum creatinine concentration is widely used to estimate creatinine clearance (Clcr), a...