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Updated: Jun 21, 2026

An Explant Assay for Assessing Cellular Behavior of the Cranial Mesenchyme
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在CHDFIDD小鼠模型中的早期胚胎发生显示了面部裂和改变的头骨神经发生

Marek Hampl1,2, Nela Jandová1,2, Denisa Lusková1

  • 1Laboratory of Molecular Morphogenesis, Institute of Animal Physiology and Genetics, Czech Academy of Sciences, 60200 Brno, Czech Republic.

Disease models & mechanisms
|March 21, 2024
PubMed
概括

在CDK13基因的突变导致CDK13相关的疾病,影响面发育. 这项研究揭示了CDK13的存在.

关键词:
轴子 轴子 轴子在CDK13中使用CDK13.头骨面部的发展神经质突发生长的增长.面部或脸部的裂.三胞胎节的三胞胎节.

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相关概念视频

Gastrulation01:56

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Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata will form...