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Updated: Jun 30, 2025

Real-time Monitoring of Mitochondrial Respiration in Cytokine-differentiated Human Primary T Cells
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Real-time Monitoring of Mitochondrial Respiration in Cytokine-differentiated Human Primary T Cells

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记忆/活跃的T细胞激活与酸盐酸酶缺乏细胞癌的免疫治疗反应有关

Junru Chen1, Xu Hu1, Junjie Zhao1

  • 1Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.

Clinical cancer research : an official journal of the American Association for Cancer Research
|March 21, 2024
PubMed
概括

酸酸酶缺乏细胞癌 (FH缺乏RCC) 治疗情况正在改善. 免疫检查点抑制剂加上氨酸激酶抑制剂 (ICI+TKI) 的组合疗法在转移性疾病中显示出优异的结果.

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The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
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