在患有性综合征的儿童中,冠状血管度指数和冠状血管结构变化
Wenbo Zhang1, Junmeng Li1, Lei Zhu2,3
1Department of Ophthalmology, Peking University First Hospital, Beijing, China.
Translational vision science & technology
|March 21, 2024
概括
患有性综合征的儿童表现出降低的冠状血管度指数 (CVI),表明与病严重程度相关的冠状血管变化. 这项研究强调了眼睛在脏综合征中的参与.
科学领域:
- 眼科医生 眼科 眼科
- 儿科 儿科 儿科
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 病综合征可能导致全身并发症.
- 在儿科性综合征中,冠状腺结构变化尚不清楚.
研究的目的:
- 为了研究患有性综合征的儿童的胸腔血管度指数 (CVI) 和胸腔结构变化.
- 为了将CVI与性综合征的临床参数相关联.
主要方法:
- 在45名患有综合征的儿童和40名对照儿童的横截面研究中.
- 增强的深度成像-光学连贯性断层扫描 (EDI-OCT) 用于胸腔成像.
- 基于深度学习的自动细分用于胆道体积 (CV),血管体积 (VV) 和CVI计算.
主要成果:
- 患有性综合征的儿童CV显著增加 (P=0.024) 但VV没有显著变化 (P=0.971).
- 与对照组相比,在患有性综合征的儿童中观察到CVI显著下降 (P<0.001).
- CVI与血清蛋白和24小时尿量正相关,与脂质和尿蛋白指标负相关.
结论:
- 在患有性综合征的儿童中,冠状血管度指数 (CVI) 显著降低.
- 降低CVI与脏疾病的严重程度相关,这表明冠状腺的参与.
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