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移植名单上的多囊性病患者的本源切除术:如何以及何时?
Sidar Copur1, Lasin Ozbek1, Mustafa Guldan1
1Department of Medicine, Koc University School of Medicine, Istanbul, Turkey.
Journal of nephrology
|March 21, 2024
概括
自体主导性多囊性病 (ADPKD) 患者经常需要进行移植. 本综述研究了在接受移植的ADPKD患者中进行本源性切除术的必要性和最佳时间.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 移植手术 移植手术
- 遗传学 遗传学 是一个
背景情况:
- 自体主导多囊性病 (ADPKD) 是最常见的遗传性病.
- 在移植等待名单中,ADPKD患者约占移植等待名单的10%.
- 在ADPKD中,出血,感染和扩大等并发症是常见的.
研究的目的:
- 审查当前关于ADPKD患者需要本地切除术的证据.
- 评估切除术的最佳时间与ADPKD患者的移植有关.
主要方法:
- 现有文献的叙述性审查.
- 对移植前和同时进行切除术的研究结果的分析.
- 评估并发症率和功能结果.
主要成果:
- 移植前切除术可以减少感染并发症,但可以延长住院时间,并导致功能丧失.
- 与最初的担忧相反,同时进行切除和移植可能不会显著增加术后并发症或持续时间.
- 关于在ADPKD患者中例行切除术的益处和风险的证据仍在争论中.
结论:
- 在接受移植的ADPKD患者中进行本地切除术的决定需要仔细考虑个体患者的因素.
- 需要进一步的研究,以确定关于切除术的时间和必要性的最终指导方针.
- 平衡原生并发症与手术风险的风险对于优化移植结果至关重要.
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