在法布里脏病中损伤的致病途径:免疫细胞透,细胞亡和纤维化之间的相互作用

Constanza Bondar1, Maria de Los Angeles de Bolla2, Pablo Neumann3

  • 1Departamento de Ciencias Biológicas, Facultad de Ciencias Exactas, CONICET, Asociado CIC PBA, Instituto de Estudios Inmunológicos y Fisiopatológicos (IIFP), Universidad Nacional de La Plata, Bv 120 Nro 1489, 47 y 115, 1900, La Plata, Argentina.

Journal of nephrology
|March 21, 2024
PubMed
概括

在法布里病中,CD163+巨细胞通过诱导TGF-β1和管状细胞亡,导致纤维化. 这一发现突显了法布里病病原体的新机制.

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