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减肥手术后使用抗肥胖药物:对大型国家数据库的分析

Stephen A Firkins¹, Vibhu Chittajallu², Bailey Flora¹

¹Digestive Diseases and Surgery Institute, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH, 44195, USA.

Obesity surgery

|March 21, 2024

概括

抗肥胖药物 (AOMs) 在减肥手术后未得到充分利用,尽管重量显著恢复. 这项研究分析了超过59,000名患者的AOM趋势,突出了差异以及需要在手术后更多地考虑这些药物的需要.

科学领域:

腹部外科腹部外科
药理学药理学是指药理学的学科.
肥胖医学肥胖医学

背景情况:

有相当数量的患者经历了低于最佳的减肥或减肥手术后恢复体重.
关于使用抗肥胖药物 (AOM) 在腹部外科手术后的文献有限.

研究的目的:

确定在经过减肥手术的患者中使用AOM的患病率和趋势.
为了确定人口和并发症相关的模式在AOM处方后减肥手术.

主要方法:

利用IBM Explorys®数据库识别了先前经过Roux-en-Y胃绕道或袖子胃切除术的成年患者.
确定的患者在手术后的五年内处方了特定的AOMs (西马格卢提德,利拉格卢提德,托皮拉,芬特明/托皮拉,纳尔特雷克松/布普罗,奥利斯塔特).
分析了不同年龄组,人口统计和并发症状况的AOM使用情况.

主要成果:

托皮拉是最常见的AOM (8%),其次是利拉格卢提德 (2.9%) 和芬特明/托皮拉 (1.03%).
使用率因年龄而异,在不同年龄段的不同AOM中使用率最高.
非洲裔美国人种族和诸如高血压,高脂血症和糖尿病等并发症与更高的AOM使用有关.

结论:

抗肥胖药物在经历不足减肥或减肥手术后恢复体重的患者中使用量明显不足.
必须解决AOM使用后腹腔外科手术的障碍.
在减肥手术后体重管理结果不充分的患者中,应更频繁,更早地考虑AOM.

关键词:

抗肥胖药物抗肥胖药物腹症腹症是指腹症.在Roux-en-Y的胃旁路术中.袖子胃切除术是什么意思减肥的方法减肥的方法减肥的方法

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