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Updated: Jun 30, 2025

Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues
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Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues

Published on: July 14, 2015

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实现可解释的相互作用预测:将生物层次结构嵌入到超标相互作用空间中

Domonkos Pogány1, Péter Antal1

  • 1Department of Measurement and Information Systems, Budapest University of Technology and Economics, Budapest, Hungary.

PloS one
|March 21, 2024
PubMed
概括

这项研究引入了可解释的药物向相互作用预测模型,通过将生物层次结构集成到超标潜伏空间中. 这种方法提高了模型的可解释性,并有助于药物发现,而不会牺牲预测准确性.

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