儿童血液溶解在急诊室:患病率,危险因素和临床影响
Nicholas Mielke1, Ray Lee2, Amit Bahl3
1Creighton University School of Medicine, Omaha, Nebraska, United States of America.
PloS one
|March 21, 2024
概括
血液化实验室样本在儿科急诊室很常见,影响了14%的遭遇. 放置在手或手腕中的外周静脉导管 (PIVC) 会增加婴儿血液溶解风险和PIVC衰竭.
科学领域:
- 儿科急救医学 儿科急救医学
- 临床病理学 临床病理学
- 实验室科学 实验室科学
背景情况:
- 血液溶解,红细胞的分解,是实验室样本采集的常见问题.
- 关于儿科急诊室 (ED) 血液化样本的患病率和风险因素的数据有限.
- 了解血液溶解对于准确的儿童诊断测试至关重要.
研究的目的:
- 为了确定血液化实验室样本在儿科ED环境中的患病率.
- 为了确定与样本血液溶解相关的风险因素.
- 评估血液溶解的临床影响,包括其对外周静脉导管 (PIVC) 失效的影响.
主要方法:
- 在密歇根州底特律市进行了一项多地观测队列研究.
- 包括接受PIVC安置和实验室检测的儿科患者 (<18岁).
- 血液溶解的存在,危险因素和PIVC失败是主要和次要结局.
主要成果:
- 在10,462次接触中,有14.0%的样本发生了血液溶解.
- 婴儿 (0-1岁) 的血液溶解率最高 (20.1%)
- 手/手腕中的PIVC与幼儿/儿童的血液溶解增加以及婴儿的失败率更高有关.
结论:
- 血液溶解是儿科ED的常见并发症,发生率与成年人相似.
- 手/手腕PIVC放置与更高的血液溶解和PIVC失败风险有关.
- 建议考虑替代PIVC场所,并进一步研究儿科血解含义.
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