超高压氧疗法在死软组织感染中的当代国家结果
William Toppen1, Nam Yong Cho2, Sohail Sareh2
1Division of Hyperbaric Medicine, Department of Emergency Medicine, University of California San Diego, San Diego, CA, United States of America.
PloS one
|March 21, 2024
概括
在死亡软组织感染 (NSTI) 中,高压氧疗法 (HBOT) 与死亡率和截肢率的降低有关. 虽然HBOT增加了住院时间和费用,但它改善了NSTI患者的治疗结果.
科学领域:
- 医学 医学 医学 医学 医学
- 外科手术 手术手术
- 关键的护理关键的护理
背景情况:
- 高压氧气疗法 (HBOT) 在死软组织感染 (NSTI) 中的作用得到了有限的回顾性数据的支持.
- 之前的研究表明,HBOT可能会降低NSTI患者的死亡率.
研究的目的:
- 研究HBOT在NSTI患者中的当代作用和结果.
- 评估HBOT与死亡率,截肢率和医疗资源利用率的关联.
主要方法:
- 对2012-2020年国家住院样本 (NIS) 数据库的回顾性分析.
- 包括60481名接受手术的NSTI患者,其中600名接受HBOT.
- 多变量回归分析以调整基线差异并评估结果.
主要成果:
- HBOT与医院住院死亡率 (AOR 0.22) 和截肢率 (AOR 0.73) 显著降低相关.
- 接受HBOT的患者经历了更长的住院时间 (增加1.6天) 和更高的成本 (增加7,800美元).
- 此外,HBOT还与非家庭出院风险降低有关 (AOR 0.79).
结论:
- 在NSTI患者中,HBOT与降低死亡率,截肢和出院到非家庭设施有关.
- 在NSTI中,HBOT的好处是逗留时间的延长和医疗保健成本的增加.
- 这些发现支持在管理NSTI时继续评估和利用HBOT.
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