人类乳头瘤病毒导致的头癌在印度-一个系统性审查和元分析
Nandimandalam Venkata Vani1, Ranganathan Rama1, Rajendran Madhanagopal1
1Department of Epidemiology, Biostatistics and Tumour Registry, Cancer Institute (WIA), Chennai, India.
JCO global oncology
|March 21, 2024
概括
人类乳头瘤病毒 (HPV) 与印度20%的头癌有关. 虽然HPV对口腔喉癌和喉癌有很大的贡献,但它在口腔癌中的作用很小.
科学领域:
- 在瘤学瘤学.
- 病毒学 病毒学
- 流行病学 流行病学
背景情况:
- 头部和部癌症 (HNC) 在印度代表着重大的全球健康负担.
- 印度高危粘膜体人类乳头瘤病毒 (HPV) 在HNC病因中的作用需要进一步阐明.
- 这项研究系统地审查了印度HNC患者的HPV患病率及其归因部分.
结论:
- 在印度,HPV在相当一部分口腔喉癌和喉癌中起着重要作用.
- 在口腔癌中HPV的致病作用似乎可以忽略不计.
- 需要进一步的研究来澄清HPV在OPC和LC中确切的致病作用,考虑到与其他风险因素的相互作用.
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