增加年癌症发病率患者年龄20-49年:一个真实数据研究
Nuria Ribelles1, Javier Pascual1,2, Laura Galvez-Carvajal1
1Medical Oncology Intercenter Unit, Regional and Virgen de la Victoria University Hospitals, IBIMA, Malaga, Spain.
JCO global oncology
|March 21, 2024
概括
在年轻人群中,癌症发病率正在上升,早期发病的癌症在几种瘤类型中比晚发病的癌症增加得更高. 这一趋势凸显出越来越多的公共卫生问题需要注意.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 基于人口的研究表明,在50岁以下的个体中,特定瘤的发病率正在上升 (早期发病的癌症,EOC).
- 有限的现实数据存在于早期发病癌症 (EOC) 发病率的趋势.
- 这项研究使用非人口登记册调查了跨代瘤发病率的变化.
研究的目的:
- 分析一代又一代不同瘤发病率的变化.
- 为了在现实世界中比较早期癌症 (EOC) 与晚期癌症 (LOC) 的发病率趋势.
主要方法:
- 一项横截面研究分析了1998年至2021年间在西班牙一所大学医院诊断的18种瘤.
- 每年确定EOC (<50年) 和LOC (≥50年) 的比例.
- 计算了年均百分比变化 (APC) 和平均APC (AAPC) 来评估发病率趋势.
主要成果:
- 该研究包括24,596名患者:22.2%的EOC和77.8%的LOC.
- 在EOC和LOC组中,整体瘤发病率增加.
- 在头部,结肠,丸,非霍奇金淋巴瘤,直肠,脏和肉瘤中,EOC的AAPC增加明显高于LOC.
结论:
- 这些发现与现有的有关早期发病癌症 (EOC) 发病率增加的数据一致.
- 越来越多的EOC发病率是一个重要的全球公共卫生问题.
- 迫切需要注意解决和减轻年轻人群中癌症的增加.
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