累积血压预测了2型糖尿病患者中风的风险
Rukai Yang1, Hejun Jiang1, Zhenhua Xing1
1Department of Cardiology, The Second Xiangya Hospital of Central South University, Changsha, China.
Diabetes & metabolic syndrome
|March 21, 2024
概括
累积系统血压 (SBP) 有效地预测了2型糖尿病 (T2D) 患者的中风. 这项测量为T2D中风风险提供了比基线BP更好的预测洞察力.
科学领域:
- 心血管医学 心血管医学
- 内分泌学 在内分泌学.
- 流行病学 流行病学
背景情况:
- 2型糖尿病 (T2D) 显著增加了心血管疾病的风险.
- 脑卒中是T2D患者的主要并发症.
- 准确预测中风风险对于T2D患者的有效管理至关重要.
研究的目的:
- 研究累积血压 (BP) 对T2D患者中风发病率的预测能力.
- 将累积血压的预测值与对中风风险的基线血压测量进行比较.
主要方法:
- 来自"控制糖尿病心血管风险的行动" (ACCORD) 试验的数据分析.
- 包括没有先前中风史的参与者.
- 评估累积BP升高和使用多变量调整的Cox比例危险模型进行评估.
主要成果:
- 分析了8282名参与者 (62.10%是男性,平均年龄为62.73岁).
- 累积的缩血压 (SBP) 和脉压独立预测了中风事件.
- 在累积血压和中风风险之间观察到显著的剂量反应关系.
结论:
- 累积SBP是T2D患者中风的独立预测因子.
- 累积SBP提供了超出基线BP评估中风风险的增量预测值.
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