预防产前和产后的孕产妇发病率和死亡率,特别是在低收入和中等收入国家
Nnabuike Chibuoke Ngene1, Jagidesa Moodley2
1Department of Obstetrics and Gynaecology, Rahima Moosa Mother and Child Hospital, Johannesburg, Gauteng, South Africa; Department of Obstetrics and Gynaecology, School of Clinical Medicine, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, Gauteng, South Africa.
孕前 (PE) 是一种复杂的妊娠障碍. 阿司匹林有效地预防早期发病的PE,而由于社会经济影响,管理需要多部门的合作伙伴关系.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 生殖生物学 生殖生物学
背景情况:
- 孕前 (PE) 是一种异质的妊娠高血压疾病.
- 胎盘功能障碍,包括不充分的子宫螺旋动脉重塑和同胞细胞应激,是早期发病PE的关键.
- 晚期发病的PE可能源于胎盘过度生长或衰老,与肥胖,糖尿病,多胎妊娠和晚期母亲年龄相关的发病率增加.
研究的目的:
- 总结一下我们对孕前的病理生理学的理解.
- 审查目前的预测方法和预防策略.
- 突出社会经济因素对PE管理的影响.
主要方法:
- 文献综述和综合目前关于子宫前的研究.
- 对早期和晚期发作的PE病理生理机制的分析.
- 预测工具和预防干预措施的评估,包括阿司匹林的疗效.
主要成果:
- 不足够的螺旋动脉改造和同胞细胞应力统一了早期发病的PE.
- 胎盘的过度生长或衰老与晚期发作的PE有关.
- 使用多模式预测工具 (风险因素,生物标志物,超声波);阿司匹林对早期发育前列腺预防有效.
结论:
- 孕前的复杂性需要了解早期和晚期发病形式的独特病理生理路径.
- 多模式预测和有针对性的预防,如阿司匹林用于早期发病的PE,至关重要.
- 通过多部门伙伴关系解决社会经济和文化因素对于减轻PE和湿的不良结果至关重要.
更多相关视频
14:43A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
Published on: January 12, 2018
12:02Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption
Published on: July 30, 2016
相关概念视频
Errors occurring during blood pressure monitoring
Several factors...
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Levels of Health Promotion and Illness Prevention
In primary prevention, actions taken before disease onset prevent the disease from...
Preventive Healthcare Services
Methods Of Healthcare Delivery System
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...
Hormonal Regulation
