20182020

Asena Avci Akca1, Lewis Couchman2, Anca Frinculescu3

  • 1Department of Biology, Akdeniz University, Antalya, Turkiye; Institute of Forensic Sciences, Department of Forensic Toxicology, Ankara University, Ankara, Turkiye; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

PubMed
概括

新型精神活性物质 (NPS) 在监狱中越来越令人担忧. 这项研究开发了一种在纸样本上识别NPS的方法,发现合成大麻素受体激动剂 (SCRA) 是最常见的,在监狱人口统计学中药物趋势各不相同.

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Drug Concentrations: Measurements

Drug concentration is the quantity of a drug present in a biological sample. Measuring drug amounts in biological samples allows the clinician to understand how a drug is absorbed, distributed, metabolized, and excreted. Samples can be obtained through invasive or non-invasive methods. Invasive techniques involve surgical or parenteral interventions to gather blood, cerebrospinal fluid, or tissue biopsy. Conversely, non-invasive approaches provide samples like urine, feces, and saliva.
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Drug Control Governance: Regulatory Bodies and Their Impact

Drug control governance involves the oversight and regulation of pharmaceuticals to ensure their safety and efficacy while preventing illegal drug use and trafficking. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Union's European Medicines Agency (EMA), play a central role in this process. These agencies evaluate the safety and efficacy of drugs before they can be marketed. They fund clinical trials and assess the benefits and risks associated with...
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Analysis of Population Pharmacokinetic Data01:12

Analysis of Population Pharmacokinetic Data

Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
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Methods for Studying Drug Absorption: In vitro01:16

Methods for Studying Drug Absorption: In vitro

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Methods for Studying Drug Absorption: In situ01:09

Methods for Studying Drug Absorption: In situ

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