莱昂林通过激活PPARγ和抑制TLR4/NF-κB/TNF-α通路来减轻万科米辛的毒性

Xuedong Yin1, Qian Gao1, Chensuizi Li1

  • 1Department of Pharmacy, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China; School of Medicine, Shanghai Jiao Tong University, Shanghai 200125, China.

概括

莱昂氨酸 (Leo) 通过减少氧化应激和炎症来保护免受万科米辛 (VCM) 诱导的损伤. 这项研究揭示了Leo激活PPARγ,为VCM毒性提供了潜在的治疗策略.

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