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Updated: Jun 30, 2025

Analyzing the Parkinson's Disease Mouse Model Induced by Adeno-associated Viral Vectors Encoding Human α-Synuclein
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Analyzing the Parkinson's Disease Mouse Model Induced by Adeno-associated Viral Vectors Encoding Human α-Synuclein

Published on: July 29, 2022

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人工智能驱动的药物重新定位揭示了efavirenz作为α-synuclein传播的调节器:对帕金森病的影响

Jae-Bong Kim1, Soo-Jeong Kim2, Minyoung So3

  • 1Department of Pharmacology, Ajou University School of Medicine, Suwon, Korea; Center for Convergence Research of Neurological Disorders, Ajou University School of Medicine, Suwon, Korea; Neuroscience Graduate Program, Department of Biomedical Sciences, Ajou University School of Medicine, Suwon, Korea.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|March 21, 2024
PubMed
概括

一种艾滋病毒药物Efavirenz在帕金森病 (PD) 中表现有前途. 这项人工智能研究发现,它减少了α-synuclein的传播和神经炎症,为PD提供了新的治疗途径.

关键词:
药物重新定位 药物重新定位埃法维伦兹 (Efavirenz) 是一种帕金森病是帕金森氏症的一种疾病.α-synuclein 是一种同核蛋白.

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