主要的第三眼皮淋巴瘤与狗的攻击性局部行为
Vanessa de C Pereira1, Luan C Henker1, Jean C O Menegatt1
1Setor de Patologia Veterinária, Departamento de Patologia Clínica Veterinária, Faculdade de Veterinária (FAVET), Universidade Federal do Rio Grande do Sul (UFRGS), Av. Bento Gonçalves, 9090, Pr. 42505, Porto Alegre, Brazil; Programa de Pós-Graduação em Ciências Veterinárias, Faculdade de Veterinária (FAVET), Universidade Federal do Rio Grande do Sul (UFRGS), Av. Bento Gonçalves, 9090, Porto Alegre, Brazil.
Topics in companion animal medicine
|March 21, 2024
概括
一个罕见的狗第三眼淋巴瘤病例显示,手术后出现了侵略性的局部复发. 这种额外的B细胞淋巴瘤强调了在犬眼瘤学中需要警监测的必要性.
科学领域:
- 兽医病理学 兽医病理学
- 狗类瘤学 狗类瘤学
- 眼睛中的新生体.
背景情况:
- 淋巴瘤是一种常见的犬类造血性瘤,但初级的第三只眼参与是罕见的.
- 粘膜相关淋巴组织的边缘区域淋巴瘤是这个位置最常见的亚型,通常是惰的.
研究的目的:
- 报告一只罕见的第三眼原发性淋巴瘤病例.
- 描述临床,宏观,组织学和免疫组织化学发现.
- 为了描述这种额外淋巴瘤的行为和免疫类型.
主要方法:
- 第三个眼结的外科切除.
- 术后监测复发的情况.
- 复发性质量的宏观和组织学检查.
- 对瘤淋巴细胞的免疫组合化学分析 (PAX5,CD20,CD79a,CD3).
主要成果:
- 一只小狗出现了第三只眼的结节,在切割后迅速复发.
- 复发性质量显示了轨道组织和眼睛的侵略性局部入侵.
- 组织学揭示了具有B细胞免疫表型 (PAX5 +,CD20 +,CD79a +,CD3-) 的中等到大型瘤淋巴细胞的片.
- 这种瘤被诊断为第三只眼的原发性外节B细胞淋巴瘤.
结论:
- 主要的第三眼皮淋巴瘤可以在狗中表现出局部侵略性的行为.
- 早期的外科干预可能无法防止迅速的复发和入侵.
- 这一案例凸显了对狗的轨道瘤及时诊断和表征的重要性.
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