腹腔镜胃切除术后术后并发症的增加,这些并发症发生在患有维护比率受损螺旋计的患者中
概括
保持比率受损螺旋计 (PRISm) 和小呼吸道功能障碍 (SAD) 增加了腹腔镜胃切除术后手术后肺部并发症的风险. 识别这些情况对于患者风险评估和管理至关重要.
科学领域:
- 肺部医学 肺部医学
- 外科手术的结果
- 呼吸系统生理学 呼吸系统生理学
背景情况:
- 保留比率受损螺旋计 (PRISm) 与增加呼吸道和全身疾病风险有关.
- 目前对PRISm对腹腔镜胃切除术 (LG) 患者短期结果的影响知之甚少.
- PRISM,小呼吸道功能障碍 (SAD) 和LG后的结果之间的关联需要进一步调查.
研究的目的:
- 调查PRISm和SAD与手术后肺部并发症 (PPC) 之间的关联,在接受LG的患者中.
- 确定PRISm和SAD是否是LG之后的PPC的独立风险因素.
- 分析基线肺功能对LG患者短期结果的影响.
主要方法:
- 预计将在2021年1月至2023年8月期间招收830名接受LG治疗的患者.
- 手术前的螺旋计将患者分类为正常,PRISm和SAD组.
- 单变量和多变量分析以评估PPC的风险因素.
主要成果:
- 在16.6%的患者中存在PRISM,在20.4%的患者中存在SAD.
- 与正常组 (9.8%) 相比,PPCs在SAD (20.3%) 和PRISm (28.0%) 组显著更高.
- SAD (OR 2.34) 和PRISM (OR 3.26) 都是PPC的独立风险因素;肺炎是最常见的PPC.
结论:
- 在接受胃癌LG治疗的患者中,PRISm和SAD显著与术后肺部并发症的增加有关.
- 这些发现凸显了手术前螺旋计的重要性,以确定患有PPC风险较高的患者.
- 早期识别和管理PRISm和SAD可能会改善LG患者的治疗结果.
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