[对身体活动与成年人缺血性中风之间的关联进行前性研究]
1Department of Chronic and Non-communicable Disease Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.
概括
定期体育活动显著降低了成年人缺血性中风的风险. 增加体力活动水平,以每天代谢等效 (MET) 小时来衡量,与中风发病率降低有关.
科学领域:
- 流行病学 流行病学
- 心血管健康 心血管健康
背景情况:
- 缺血性中风是全球死亡和残疾的主要原因.
- 了解可修改的风险因素,如身体活动,对于预防策略至关重要.
- 以前的研究表明,身体活动与中风风险降低之间存在联系,但需要更多的数据.
研究的目的:
- 调查身体活动水平与缺血性中风发病率之间的潜在关联.
- 在成年人群中量化与不同水平的体力活动相关的风险降低.
主要方法:
- 利用了来自中国Kadoorie生物库研究的数据,其中包括53916名30-79岁的参与者.
- 采用Cox比例危险回归模型来分析基线身体活动与缺血性中风风险之间的关系.
- 根据每天的代谢等价 (MET) 小时测量的身体活动水平,将参与者分为五分之一.
主要成果:
- 在平均11.4年的随访期间,记录了2220次缺血性中风事件.
- 与最低体力活动群 (<16.17MET-h/d) 相比,较高的活动水平与降低缺血性中风风险有关.
- 缺血性中风的危险比率随着体力活动的增加而逐渐降低,最高五分位数 (≥43.87MET-h/d) 显示24%的风险降低 (HR:0.76,95%CI:0.64-0.89).
结论:
- 较高的体力活动水平有望与发生缺血性中风的风险显著降低相关.
- 促进增加体力活动可以是预防缺血性中风的有效策略.
- 这些发现支持旨在增加身体活动的公共卫生倡议,以打击中风的负担.
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