相关实验视频
Updated: May 8, 2026

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
用Infliximab治疗的克罗恩病患者的乳病:一个病例报告
Mansour Altuwaijri1, Nasser Alkhraiji2, Mosaab Almasry2
1Division of Gastroenterology, Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
本案例研究详细介绍了克罗恩氏病患者在生物药物治疗中首次诊断出牛病的病例. 治疗包括暂停infliximab和azathioprine,然后在布鲁塞拉治疗后恢复它们.
科学领域:
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 克罗恩病 (Crohn's disease,简称CD) 是一种慢性炎症疾病,影响肠道.
- 生物疗法,包括抗瘤坏死因子 (抗TNF) 药物,是常见的CD治疗方法.
- 生物药物可以增加机会性感染风险,但严重感染的数据有限.
研究的目的:
- 在接受生物药物和免疫调节剂治疗的克罗恩病患者中报告第一个菌病例.
- 突出在这种情况下的诊断和管理挑战.
主要方法:
- 一名40岁的克罗恩氏病男性患者接受了因弗利克西马布和阿扎西奥普林治疗,出现了暗示感染的症状.
- 诊断工作包括血液培养,揭示了布鲁塞拉物种.
- 治疗包括启动抗布鲁塞拉抗生素和暂时停止免疫抑制剂.
主要成果:
- 在接受抗TNF治疗和阿扎西奥普林的克罗恩病患者中诊断出布鲁塞洛斯.
- 患者出现了包括发烧,减肥和关节疼痛在内的症状.
- 抗生素治疗病是成功的,允许最终恢复infliximab和azathioprine.
结论:
- 这一案例强调了在免疫功能低下的患者中考虑罕见感染的重要性,比如在免疫功能低下的患者中考虑血病.
- 管理需要多学科的方法,包括胃肠科医生和传染病专家.
- 布鲁塞洛症的成功治疗使得克罗恩病的基本疗法能够继续使用.
更多相关视频
相关概念视频
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF
Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease III: Crohn's Disease
Inflammatory Bowel Disease IV: Clinical Manifestations

