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Updated: Jun 30, 2025

Solid-phase Synthesis of [4.4] Spirocyclic Oximes
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Published on: February 6, 2019

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循环氨单氧化酶的结构导向进化向大容量欧米硫化物:基质迁移和立体选择性反转

Shiyu Wei1,2, Guochao Xu2, Jieyu Zhou2

  • 1Institution: School of Biological and Pharmaceutical Engineering, Lanzhou Jiaotong University, Address, Lanzhou Jiaotong University, Lanzhou, 730070, Gansu, China.

Chemphyschem : a European journal of chemical physics and physical chemistry
|March 21, 2024
PubMed
概括

结构引导的工程 Amycolatopsis methanolica CHMO (AmCHMO) 增强的不对称硫化. 突变将立体选择性从R逆转为S,为梅硫化物生产实现了高反体过量.

关键词:
(S) - 奥梅普拉 (S) - 奥梅普拉 (S) - 奥梅普拉 (S) - 奥梅普拉 (S) - 奥梅普拉 (S) - 奥梅普拉 (S) - 奥梅普拉 (S) - 奥梅普拉 (O)循环赫萨农单氧化原酶.模拟MD的模拟方法立体选择性的反转.基质迁移是基质的迁移

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