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Updated: Jun 30, 2025

Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test OGTT and Insulin Tolerance Test ITT
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三甲基胺N-氧化物损害β细胞功能和葡萄糖耐受性

Lijuan Kong1,2,3, Qijin Zhao1,2,3, Xiaojing Jiang1,2,3

  • 1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Nature communications
|March 22, 2024
PubMed
概括

三甲基胺N氧化物 (TMAO) 损害了葡萄糖刺激的胰岛素分泌和β细胞功能,导致2型糖尿病. 抑制TMAO的产生可能为糖尿病管理提供新的治疗策略.

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