评估使用集群随机化对自闭症谱系障碍的查
Sigridur Loa Jonsdottir1,2, Evald Saemundsen3,4, Elin Astros Thorarinsdottir5,6
1State Diagnostic and Counseling Center, Dalshraun 1B, 220, Hafnarfjordur, Iceland. sigridur.l.jonsdottir@rgr.is.
Scientific reports
|March 22, 2024
概括
冰岛的一项针对自闭症谱系障碍 (ASD) 的查计划显示,受邀组的发病率更高. 然而,宽的置信区间意味着需要更多的研究来确认查是否比常规护理更有效.
科学领域:
- 儿科 儿科 儿科
- 儿童心理学 儿童心理学
- 公共卫生 公共卫生
背景情况:
- 自闭症谱系障碍 (ASD) 诊断依赖于行为观察和发展史.
- 早期发现ASD对于及时干预和改善结果至关重要.
- 查计划在识别自闭症方面的有效性需要持续评估.
研究的目的:
- 将被邀请参加查计划的儿童与接受常规护理的儿童的自闭症谱系障碍 (ASD) 发病率进行比较.
- 在初级卫生保健机构内评估针对性ASD查计划的诊断收益.
- 评估一个集群随机查干预对ASD检测率的影响.
主要方法:
- 在冰岛进行了一项集群随机试验,涉及7173名30个月龄的儿童.
- 干预组的儿童被邀请参加专门的ASD查计划.
- 对照组接受了标准的健康儿童护理;在为期两年的随访中,使用ICD-10标准的跨学科团队证实了诊断.
主要成果:
- 整个ASD的累积发病率为1.66%.
- 与对照组 (1.83%,1.02%) 相比,受邀组的发病率较高 (2.13%).
- 发病率的置信区间很宽,限制了关于查有效性的最终结论.
结论:
- 虽然查计划在邀请组中发现了更高的自闭症发病率,但结果从统计学上来说并不具有决定性.
- 该研究强调需要进一步研究这种ASD查方法的有效性.
- 这些发现强调了自闭症检测的复杂性和强大的诊断过程的重要性.
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