在心脏病门诊患者中,相角与内脏脂肪和心脏代谢风险有关吗?
Victoria Domingues Ferraz1, Jarson Pedro da Costa Pereira2, Claudia Porto Sabino Pinho Ramiro3
1Departament of Nutrition, Federal University of Pernambuco, Prof. Moraes Rego Avenue, 1235 - Cidade Universitária, Recife, Pernambuco, 50670-901, Brazil.
European journal of clinical nutrition
|March 22, 2024
概括
阶段角 (PhA) 与心脏病患者的内脏脂肪组织 (VAT) 和心血管风险相反相关. 这一发现突出了PhA的发现.
科学领域:
- 心血管健康中的生物标志物
- 身体组成分析 身体成分分析
- 代谢综合征研究 代谢综合征研究
背景情况:
- 阶段角 (PhA) 是一种与细胞健康和氧化应激相关的公认预后指标.
- PhA,脂肪和心血管风险因素之间的关系需要进一步调查,特别是在临床心脏病患者群体中.
研究的目的:
- 检查相角 (PhA) 与主要代谢,脂肪和心血管风险参数之间的关联.
- 评估PhA的实用性,作为对心脏代谢健康评估的补充标记在心脏病诊断的门诊患者.
主要方法:
- 该研究包括来自心脏病科的105名成年门诊患者 (26-59岁).
- 通过超声波评估内脏脂肪组织 (VAT);使用生物电阻分析 (BIA) 计算相角 (PhA).
- 评估的体重指数,腰围,腰与身高的比,肌肉强度和弗雷明汉风险评分.
主要成果:
- 在较高的PhA值与增加的VAT和心血管风险 (调整后OR分别为0.79和0.74) 之间发现了显著的反向关联.
- 较低的PhA值与高的增值税 (AUC:0.82) 有着强烈的关联,与较高的心血管风险 (AUC:0.70) 有着相当的关联.
结论:
- 阶段角 (PhA) 独立且反向地与内脂肪组织 (VAT) 和心血管风险的增加有关.
- PhA显示出作为评估风险人群心脏代谢健康的有价值的非侵入性标记物的潜力.
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