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Updated: Jun 12, 2026

A Fluorogenic Peptide Cleavage Assay to Screen for Proteolytic Activity: Applications for coronavirus spike protein activation
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确定FasL作为推动COVID-19病理和致死性的关键宿主因素

Marie-Christine Albert1,2, Iratxe Uranga-Murillo3,4,5, Maykel Arias3,4,5

  • 1Cell death, inflammation and immunity laboratory, CECAD Cluster of Excellence, University of Cologne, Cologne, 50931, Germany.

Cell death and differentiation
|March 22, 2024
PubMed
概括

严重的COVID-19涉及不受控制的炎症. 这项研究发现,通过减少细胞死亡和炎症,抑制Fas Ligand (FasL) 提高了小鼠和人类的生存率,这表明FasL是治疗点.

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