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Updated: Jun 30, 2025

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases
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Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases

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在乳腺癌患者中根据种族,年龄和临床因素对BIRC5的表达

Alina M Hamilton1,2, Andrea Walens1,3, Sarah C Van Alsten3

  • 1Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, 27599, USA.

Breast cancer research : BCR
|March 22, 2024
PubMed
概括

患有乳腺癌的黑人和年轻女性显示出更高的生存率/BIRC5表达. 高BIRC5的瘤与ER阳性病例的无复发生存率较低有关,这表明针对性治疗可以获得公平的结果.

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The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
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