研究怀孕和新生儿出生体重期间的甘油三变化以及不良结果
Hongjuan Wei1, Yinyan Tang1, Yu Xia2
1Neonatal Intensive Care Unit, Nanjing Lishui People's Hospital, Zhongda Hospital Lishui Branch, Southeast University, Nanjing, China.
概括
怀孕后期母亲的甘油三水平与高出生体重和宏观症的风险增加有关. 从中期到晚期的甘油三变化也与出生体重相关,突出了它们对胎儿发育的影响.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 新生儿健康 新生儿健康
背景情况:
- 孕产妇的甘油三度对胎儿生长至关重要.
- 中期到晚期的甘油三变化对出生体重的具体影响仍然不清楚.
研究的目的:
- 调查从怀孕中期到晚期的孕产妇甘油三变化与新生儿出生体重之间的关联.
- 检查这些甘油三变化与新生儿不良后果 (包括巨) 之间的关系.
主要方法:
- 一项包括931名怀孕妇女在妊娠年龄≥35周时单独分娩的队列研究.
- 在分娩前的中期和晚期测量了母亲的甘油三水平.
- 主要结局包括新生儿出生体重和宏观的风险.
主要成果:
- 晚期的甘油三水平与出生体重 (β=126.40,p<.001) 和宏观的风险 (OR=2.11,p=.022) 有着积极的关联.
- 中期到晚期的甘油三变化与出生体重 (β=27.58,p=.003) 有积极的关联,但没有宏观症风险 (OR=1.12,p=.178).
- 单独的中期甘油三水平与出生体重或巨症风险没有显著关联.
结论:
- 晚期孕产妇高水平的甘油三与增加出生体重和巨症风险有关.
- 从怀孕中期到晚期的甘油三的变化与出生体重有关,这表明它在胎儿生长调节中的作用.
- 进一步研究孕期甘油三形状的重要性是有必要的,以了解它们对妊娠结果的全部影响.
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