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在莫桑比克生产的玉米面粉中的亚拉托克辛及其风险评估

Martinho Gamas Dinis Martinho¹, Andrea Rebouças Rocha², Nathália Ribeiro Dos Santos²

¹Graduate Program in Food Science, College of Pharmacy, Federal University of Bahia, Salvador, Brazil.

Food additives & contaminants. Part B, Surveillance

|March 22, 2024

概括

莫桑比克的玉米面粉含有亚毒素,由于高消费,可能对健康构成潜在风险. 需要进行进一步的研究,以减轻因这种主食而暴露于亚拉托克辛的风险.

科学领域:

食品科学食品科学食品科学
毒理学毒理学毒理学
公共卫生公共卫生

背景情况:

毒素是某些模具产生的有毒化合物,可以污染粮食作物.
在许多非洲国家,玉米是主食,是潜在的亚拉托克辛暴露的重要来源.
受污染的玉米面粉引起了公众健康的担忧,原因是亚毒素的致癌性.

研究的目的:

来自莫桑比克的玉米面粉中量化阿弗拉托克辛 (B1,B2,G1和G2) 的含量.
评估与莫桑比克人口中阿弗拉托克辛消费相关的致癌风险.
为了比较检测到的 aflatoxin水平与监管最高限值.

主要方法:

从莫桑比克的五个加工厂收集了30个玉米面粉样本.
使用具有光检测的高性能液态染色学 (HPLC) 量化亚毒素.
计算暴露边际 (MOE) 以评估健康风险.

主要成果:

非洲毒素B1 (AFB1) 度在0.25至0.33μg/kg-1.1之间.
非洲毒素总含量从0.55到1.05微克每公斤-1不等,平均值为0.89微克每公斤-1.
男人和女人的计算的MOE (分别为243和231) 低于风险切线水平.

结论:

莫桑比克的玉米面粉含有亚毒素,含量低于但接近某些监管限制.
尽管MOE值低于值,但玉米面粉的高消费量表明,由于暴露于亚黄毒素,存在潜在的肝癌 (肝癌) 风险.
需要公共卫生策略来管理玉米中阿弗拉托克辛污染,玉米是关键的食物来源.

关键词:

菌类毒素 (Mycotoxins) 是一种毒素.玉米制品玉米制品莫桑比克, 粮食安全风险评估风险评估风险评估

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