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Updated: Jun 30, 2025

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作为恶性瘤个性化治疗的目标,mTOR过活和RICTOR放大

Dániel Sztankovics1, Dorottya Moldvai1, Gábor Petővári1

  • 1Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary.

Pathology oncology research : POR
|March 22, 2024
PubMed
概括

拉巴胺素 (mTOR) 途径的机械性标中的过活是癌症的关键标. 评估mTORC1/mTORC2活性对于有效的mTOR抑制剂治疗至关重要,尤其是在新的向治疗出现时.

关键词:
这就是RICTOR放大器的功效.里克托尔的表达过度.在mTOROR中使用mTOR.mTORC2 过度活动恶性瘤是一种恶性瘤.

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