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急性病毒性肝炎E感染复杂化后活着的肝脏捐赠者肝切除术恢复
Kaleem Ullah1, Sidhant Ochani2, Hafiz B Ahmad1
1Department of Liver Transplantation, Pir Abdul Qadir Shah Jeelani Institute of Medical Sciences, Gambat, Pakistan.
Journal of clinical and experimental hepatology
|March 22, 2024
概括
活着的肝脏捐赠者在手术后感染了E型肝炎病毒 (HEV),影响了恢复. 这一案例强调了对捐赠者的HEV监测的必要性,特别是在高流行率地区.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 传染性疾病 传染性疾病
- 移植免疫学 移植免疫学
背景情况:
- 活肝捐献是治疗末期肝病的关键程序.
- 捐赠者的术后并发症可能会影响恢复,并引发安全问题.
- 肝炎E病毒 (HEV) 感染是肝移植的新兴问题,包括活体供体.
研究的目的:
- 在右叶肝切除术后,报告活体肝脏捐赠者的HEV感染病例.
- 在这种情况下,要突出HEV感染的临床表现和诊断方法.
- 讨论HEV感染对捐赠者管理和接受者结果的影响.
主要方法:
- 一个28岁的男性活着的肝脏捐赠者的病例报告.
- 术后肝功能测试的临床监测.
- 血清和PCR测试用于HEV的确认.
- 提供捐赠者的支持管理.
主要成果:
- 捐赠者在术后第3天出现了和黄.
- 肝功能标志物升高在术后5天达到峰值.
- 通过血清学和PCR确认了HEV感染.
- 捐赠者在出院后恢复正常的肝功能.
结论:
- 在活着的肝脏捐赠者中,应考虑HEV感染,这些肝脏捐赠者呈现异常的术后肝功能.
- 高HEV流行地区需要对捐赠体感染的警性增加.
- 建议对肝脏捐赠者的HEV疫苗接种进行进一步研究.
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