关于前列腺原发性大细胞神经内分泌癌的系统综述
Ngan Nguyen1, Ronald Dean Franz2, Omar Mohammed3
1Hematology and Medical Oncology, The Oncology Institute of Hope and Innovation, Riverside, CA, United States.
Frontiers in oncology
|March 22, 2024
概括
前列腺的大细胞神经内分泌癌 (LCNEC) 是一种罕见的癌症. 大多数患者出现了晚期疾病和不良预后,但早期诊断和特定治疗可能会改善结果.
科学领域:
- 在瘤学瘤学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 癌症研究 癌症研究
背景情况:
- 大细胞神经内分泌癌 (LCNEC) 是一种不常见的前列腺癌亚型,特征不明.
- 它可以独立出现 (de novo) 或从前列腺腺癌转变,通常是在激素治疗后.
结论:
- 前列腺LCNEC是罕见的,往往是晚诊断的,并且通常预后不好.
- 通过手术,放射和抗雄激素剥夺疗法 (ADT) 的早期诊断可以改善结果.
- 新型治疗组合,如M6620与化疗,在特殊情况下显示出前景.
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