人是一个有机的统一:肠肺轴和肺炎
Jing Guo1,2, Le Wang3, Ningxin Han3
1Graduate School, Hebei University of Chinese Medicine, Shijiazhuang, 050090, Hebei, China.
Heliyon
|March 22, 2024
概括
肠-肺轴描述了肠和肺之间通过微生物和免疫的双向通信. 本综述探讨了其在肺炎 (包括COVID-19) 中的作用,以及潜在的治疗应用.
科学领域:
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
- 肺部病理学 肺部病理学
背景情况:
- 人体的功能是一个集成的系统,器官是相互连接的.
- 肠-肺轴是这种相互联系的典范,突出显示了胃肠道和肺之间的沟通.
研究的目的:
- 审查关于肠肺轴的当前研究.
- 定义肠肺沟通的概念和机制.
- 探索肺炎对这一轴的影响及其治疗潜力.
主要方法:
- 关于肠肺轴研究的文献综述.
- 分析涉及微生物和免疫系统的交叉交谈机制.
- 检查肺炎 (COVID-19,CAP) 对肠道微生物群和免疫功能的影响.
主要成果:
- 肠肺轴涉及肠和肺之间通过微生物和免疫系统的双向通信.
- 门静脉和中腔淋巴管是关键的沟通通路.
- 肺炎,包括COVID-19和社区获得性肺炎 (CAP),通过这个轴影响肠道微生物和免疫功能.
结论:
- 肠肺轴对于维持肠与肺之间的平衡至关重要.
- 了解这一轴,可以了解肺炎的病原性.
- 肠道微生物和肠肺轴对肺炎治疗具有治疗潜力.
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