全球关于人体器官的研究的图书统计分析
Huanyu Li1,2, Daofeng Wang3, Cheong Wong Ho4
1Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, Liaoning, 110122, China.
Heliyon
|March 22, 2024
概括
人类有机体研究正在迅速扩大,为疾病治疗提供了动物模型的替代方案. 关键领域包括组织建模,疾病机制和精密医学,未来重点是成本和标准化.
科学领域:
- 生物医学研究的研究.
- 干细胞生物学 干细胞生物学
- 再生医学是一种再生医学.
背景情况:
- 人类有机体为疾病研究和治疗提供了动物模型的有希望的替代品.
- 关于人类有机体研究的特点和趋势的全面分析很少存在.
- 该领域已经出现了指数级增长,特别是在过去十年.
研究的目的:
- 在过去二十年中对人类有机体研究进行情报分析.
- 确定研究热点,主要贡献者和新兴趋势.
- 在基础研究,生物银行,精准医学和疾病建模中绘制有机体应用的地图.
主要方法:
- 从Web of Science核心集合 (2002-2022) 中对8,591篇有机类文章进行了图书法分析.
- 利用CiteSpace软件进行情报分析,包括共同引用,共同发生,集群和突发检测.
- 将高度引用的文章分类为研究领域:基础研究,生物银行,精准医学和疾病建模.
主要成果:
- 自2009年以来,出版物产量增加了近70倍,有着重要的国际合作 (美国,中国,德国,荷兰,英国).
- 确定了关键的研究热点:组织模型和功能结构,细胞间信号传递,免疫机制和瘤转移.
- 高度引用的研究涵盖了基本的干细胞过程 (38%),生物银行 (10%),精准医学 (16%) 和疾病建模 (36%).
结论:
- 有机器人研究是一个快速发展的领域,在医学上具有显著的潜力.
- 目前面临的挑战包括成本,血管化,免疫整合,标准化和临床数据限制.
- 未来的方向强调降低成本,技术共享,国际标准和高水平的临床试验.
相关概念视频
02:03Anatomy of the Circulatory System
The human circulatory system consists of blood, blood vessels that carry blood away from the heart, around the body, and back to the heart, and the heart itself, which acts as a central pump. The systemic circuit supplies blood to the whole body, the coronary circuit supplies blood to the heart, and the pulmonary circuit supplies blood flow between the heart and lungs.
01:20Overview of the Vascular System
The vascular system comprises an extensive network of arteries, capillaries, and veins. The vascular system can be broadly divided into the blood and lymphatic systems. Typically, blood vessels can be categorized into three histological regions: tunica intima, tunica media, and tunica adventitia. The tunica intima consists of a single layer of endothelial cells attached to the basal lamina. Underlying the basal lamina is a connective tissue layer and an elastic lamina that gives stability and...
01:24Overview of Anatomy and Physiology
Human anatomy is the scientific study of the body's structures. Some of these structures are very small and can only be observed and analyzed with the assistance of a microscope. Other larger structures can readily be seen, manipulated, measured, and weighed. The word "anatomy" comes from a Greek root that means "to cut apart." Human anatomy was first studied by observing the body's exterior and the wounds of soldiers and other injuries. Later, physicians were allowed to dissect the bodies of...
01:28Imaging Studies for Cardiovascular System V: CT
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...