Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

[Intelligence level and structure in school age children with fetal growth restriction].

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics·2009
Same author

Uncoupling the D1-N-methyl-D-aspartate (NMDA) receptor complex promotes NMDA-dependent long-term potentiation and working memory.

Biological psychiatry·2009
Same author

A phospho-directed macroporous alumina-silica nanoreactor with multi-functions.

ACS nano·2009
Same author

Subintimal angioplasty for below-the-ankle arterial occlusions in diabetic patients with chronic critical limb ischemia.

Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists·2009
Same author

Natural killer/T cell lymphoma initiating with pleural effusion: the significance of MICM combined techniques for the diagnosis.

Zhongguo shi yan xue ye xue za zhi·2009
Same author

[Advance of study on animal models of lymphoma].

Zhongguo shi yan xue ye xue za zhi·2009

相关实验视频

Updated: Jun 30, 2025

Assembly and Tracking of Microbial Community Development within a Microwell Array Platform
09:24

Assembly and Tracking of Microbial Community Development within a Microwell Array Platform

Published on: June 6, 2017

9.0K

MCSS:基于结构的微生物社区模拟器.

Xingqi Hui1,2, Jinbao Yang2,3, Jinhuan Sun4

  • 1Zhengzhou Research Base, State Key Laboratory of Cotton Biology, School of Agricultural Sciences, Zhengzhou University, Zhengzhou, China.

Frontiers in microbiology
|March 22, 2024
PubMed
概括

MCSS是一种新的工具,可以模拟微生物群落并生成长时间读取的测序数据. 这有助于研究人员验证和改进复杂微生物组的元基因组分析方法.

关键词:
组装的组装组装的组装.长时间阅读阅读.甲基基因组 (metagenome) 是一个基因组.微生物群落的微生物群落.一个模拟器模拟器.

更多相关视频

Characterizing Microbiome Dynamics – Flow Cytometry Based Workflows from Pure Cultures to Natural Communities
09:57

Characterizing Microbiome Dynamics – Flow Cytometry Based Workflows from Pure Cultures to Natural Communities

Published on: July 12, 2018

11.9K
Assessing the Viability of a Synthetic Bacterial Consortium on the In Vitro Gut Host-microbe Interface
10:24

Assessing the Viability of a Synthetic Bacterial Consortium on the In Vitro Gut Host-microbe Interface

Published on: July 4, 2018

11.6K

相关实验视频

Last Updated: Jun 30, 2025

Assembly and Tracking of Microbial Community Development within a Microwell Array Platform
09:24

Assembly and Tracking of Microbial Community Development within a Microwell Array Platform

Published on: June 6, 2017

9.0K
Characterizing Microbiome Dynamics – Flow Cytometry Based Workflows from Pure Cultures to Natural Communities
09:57

Characterizing Microbiome Dynamics – Flow Cytometry Based Workflows from Pure Cultures to Natural Communities

Published on: July 12, 2018

11.9K
Assessing the Viability of a Synthetic Bacterial Consortium on the In Vitro Gut Host-microbe Interface
10:24

Assessing the Viability of a Synthetic Bacterial Consortium on the In Vitro Gut Host-microbe Interface

Published on: July 4, 2018

11.6K

科学领域:

  • 微生物学 微生物学
  • 生物信息学是一种生物信息学.
  • 基因组学就是基因组学.

背景情况:

  • 甲基因组学分析依赖于*de novo*组合来理解微生物群落.
  • 第三代测序技术 (PacBio Hi-Fi,ONT) 为组装提供了改进的数据.
  • 验证长期阅读的生物信息工具对元基因组学的验证是必要的,但具有挑战性.

研究的目的:

  • 推出MCSS,一种用于微生物群落和测序数据的新型模拟器.
  • 为基因组分析工具提供基准测试和改进资源.
  • 为了生成真实的模拟数据集,反映真实的微生物组结构.

主要方法:

  • 基于现实世界的结构属性,MCSS模拟了微生物群落.
  • 它产生合成的PacBio Hi-Fi和牛津纳米孔技术 (ONT) 长读.
  • 该工具的性能被评估为其复制社区多样性和结构的能力.

主要成果:

  • MCSS成功地产生了模拟的微生物群落,具有现实的多样性和与实际社区的结构相似性.
  • 该模拟器产生了与PacBio Hi-Fi和ONT平台兼容的合成长读数.
  • 评估证实了该工具在创建代表性微生物组数据集方面的能力.

结论:

  • MCSS是一种有价值的生物信息工具,用于模拟复杂的微生物群落,并生成长时间读取的测序数据.
  • 它解决了对可靠数据集的关键需求,以验证和增强元基因组装工具.
  • 可用性MCSS促进了微生物组研究和生物信息学工具开发的进步.