半球内和半球之间的一致活动:通过右侧后壁皮质皮质的rTMS揭示皮质-皮质连接性
Chiara Mazzi1, Sonia Mele1, Chiara Bagattini1,2
1Perception and Awareness (PandA) Laboratory, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Frontiers in human neuroscience
|March 22, 2024
概括
低频重复性跨刺激 (rTMS) 通过右后壁皮质皮质 (rPPC) 增加了大脑连接. 这种刺激增强了大脑半球内部和大脑半球之间的通信,表明了中风康复的潜力.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 康复医学 康复医学 康复医学
背景情况:
- 已知在右侧后壁皮质皮质 (rPPC) 上施加的低频 (1 Hz) 重复性横刺激 (rTMS) 可降低皮质刺激性.
- 了解rTMS对大脑连接的影响对于开发有效的治疗策略至关重要.
研究的目的:
- 为了研究1HzrTMS对rPPC对半球内和半球间皮层-皮层连接性的影响.
- 在rTMS之后,分析不同频段的EEG连贯性的变化.
主要方法:
- 14名健康参与者在rPPC (P6) 上进行了静止状态EEG,在30分钟的1HzrTMS或假刺激之前和之后进行了静止状态EEG.
- 电脑脑脑电图连贯性被计算为半球内和半球间的电极组合 (P4,P8,CP6) 在三角形,三角形,α,β,gamma频段.
主要成果:
- 在delta,theta,alpha和beta波段中观察到rPPC和逆侧同源位点之间的连贯性显著增加.
- 在theta,alpha,beta和gamma波段中,rPPC和右额头部位之间也发现了更高的连贯性,这表明前额-双侧网络激活.
- 这些发现表明,低于值的rTMS比rPPC增强皮层-皮层连接,并可能诱导抑制作用.
结论:
- 通过rPPC传输1 Hz的rTMS调节了大脑内和外半球之间的连接.
- 观察到的连贯性增加支持rTMS在皮层网络上的抑制作用.
- 这些结果对设计基于证据的康复方案产生影响,特别是对于中风后的康复.
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