需要用康复性等离子体治疗的免疫受损患者的SARS-CoV-2持续性:一个病例报告
Gabrielle Librizzi1,2, Viraj Modi2, Audun J Lier3,4
1Internal Medicine, Stony Brook University Hospital, Stony Brook, USA.
Cureus
|March 22, 2024
概括
康复性血可以帮助患有严重COVID-19的免疫功能低下患者. 早期考虑这种疗法和病毒载量监测可以指导持续的SARS-CoV-2感染的治疗决策.
科学领域:
- 免疫学 免疫学 免疫学
- 传染性疾病 传染性疾病
- 在瘤学瘤学.
背景情况:
- 免疫功能低下的患者面临SARS-CoV-2感染的严重过程.
- 接受免疫抑制治疗的毛囊淋巴瘤患者的风险较高.
- 在这种人群中,标准疗法可能不足以治疗严重的COVID-19.
研究的目的:
- 评估康复期血在患有严重COVID-19的免疫功能低下患者的疗效.
- 探索病毒载量监测在持续性SARS-CoV-2感染指导治疗中的作用.
主要方法:
- 一名76岁的男性患有卵泡淋巴瘤和COVID-19肺炎的病例报告.
- 用长时间的治疗疗程进行治疗. remdesivir.
- 在住院的第31天给药一次剂量康复期血.
- 监测SARS-CoV-2病毒载量和临床状态.
主要成果:
- 患者经历了持续的低氧化和高病毒载量,尽管remdesivir.
- 康复性血管理导致SARS-CoV-2病毒载量的改善.
- 患者得到了出院,并恢复了癌症治疗.
结论:
- 康复性血是SARS-CoV-2感染的免疫功能低下患者的潜在治疗选择.
- 早期考虑康复期血可能是有益的.
- 循环值监测可以指导持久的SARS-CoV-2感染的替代疗法决策.
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