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酶性甲基化作为ATP独立结合的工具

Jiaming Peng1, Gregory R Hughes2, Manuel M Müller2

  • 1Department of Chemistry University of Basel Mattenstrasse 24a 4002 Basel Switzerland.

Angewandte Chemie (Weinheim an der Bergstrasse, Germany)
|March 22, 2024
PubMed
概括

碳酸基质的酶催化F-甲基化产生了活性F-甲基. 这种方法使得在生理条件下能够有效合成胺,胺,硫和蛋白质修饰.

关键词:
生物催化物的生物催化.甲基转移酶生物催化剂的生物催化原生化学结合原生化学结合后翻译修改 后翻译修改蛋白质合成 蛋白质合成

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ATP and Macromolecule Synthesis01:28

ATP and Macromolecule Synthesis

Biological macromolecules are organic compounds, predominantly composed of carbon atoms. The carbon atoms are covalently bonded with hydrogen, oxygen, nitrogen, and other minor elements. There are four major biological macromolecule classes: carbohydrates, lipids, proteins, and nucleic acids.
Most macromolecules are composed of single subunits, or building blocks, called monomers. The monomers combine with each other using covalent bonds to form larger molecules known as polymers.
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