在亚马逊厄瓜多尔的原住民Shuar中,白天皮质醇模式的变化
Melissa A Liebert1, Samuel S Urlacher2,3, Felicia C Madimenos4,5
1Department of Anthropology, Northern Arizona University, Flagstaff, Arizona, USA.
概括
脑下垂体-垂体-上腺 (HPA) 轴显示,与高收入人群相比,亚马逊Shuar的皮质醇水平较低. 年龄会影响皮质醇,但性别不会,相互作用会影响白天皮质醇的下降.
科学领域:
- 人类进化生物学 人类进化生物学
- 生理学人类学生理学人类学.
- 压力生理学研究研究 压力生理学研究
背景情况:
- 脑下垂体上腺 (HPA) 轴和皮质醇是人类应激反应的关键.
- 大多数HPA轴研究发生在高收入环境中,而不是祖先环境.
- 了解HPA在不同社会生态环境中的功能至关重要.
研究的目的:
- 为了研究来自亚马逊厄瓜多尔的原住民Shuar的白天唾液皮质醇模式.
- 为了检查年龄,生物学性别和BMI对皮质醇产生的影响.
- 将皮质醇水平与高收入人群中发现的水平进行比较.
主要方法:
- 在亚马逊地区的厄瓜多尔研究了298名原住民Shuar (年龄为2-86岁).
- 连续三天,每天收集三次的唾液样本.
- 测量了醒来时的皮质醇水平,皮质醇唤醒反应,日间倾斜和总日产量.
主要成果:
- 年龄与清醒时皮质醇和总日产量正相关;青少年/青少年的水平较低.
- 生物性别没有显著预测皮质醇水平;男性和女性之间的模式是相似的.
- 年龄,性别和BMI显著相互作用,以缓解白天皮质醇下降率.
- 与高收入人群相比,Shuar参与者通常表现出较低的皮质醇度.
结论:
- 这项研究扩大了对HPA轴活动和皮质醇生产的全球变化的理解.
- 这些发现突出了人类压力生理学的可塑性,跨越了不同的发育和社会生态环境.
- 提供非工业化,高病原体环境中的皮质醇调节的关键数据.
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