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Silvia Sirotti1, Robert Terkeltaub2, Georgios Filippou1,3

  • 1IRCCS Ospedale Galeazzi - Sant'Ambrogio, Rheumatology Department, Milan, Italy.

PubMed
概括

尽管过去的努力,但仍然需要对铁酸盐沉积 (CPPD) 进行标准化命名. 重新定义CPPD术语和利用先进的成像将改善研究,患者理解和临床结果.

相关概念视频

Calmodulin-dependent Signaling01:16

Calmodulin-dependent Signaling

Calmodulin (CaM) is a calcium-binding protein in eukaryotes that controls various calcium-regulated cellular processes. It has four calcium-binding sites that bind calcium to form the calcium-calmodulin ( Ca2+-CaM) complex. GPCR stimulation increases the calcium levels in the cells that bind to CaM and induces a conformational change.
The Ca2+-CaM complex does not have enzymatic activity by itself. Instead, the complex binds downstream target proteins, including membrane proteins or enzymes,...
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