相关实验视频

Updated: Jun 30, 2025

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
12:59

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes

Published on: September 26, 2013

34.5K

在化脊柱炎中H3K27me3-介导的Th17差异化的作用

Yuening Chen1, Wanlin Liu2, Xiaohan Xu3

  • 1Department of Rheumatology, China Academy of Chinese Medical Sciences, Guang'anmen Hospital, Beijing, 100053, China.

Inflammation
|March 22, 2024
PubMed
概括

基因组3 Lys 27三甲基化 (H3K27me3) 在活性结性脊髓炎 (AS) 中降低,与增加的T辅助17 (Th17) 细胞分化有关. JMJD3/EZH2酶调节这种表观遗传修饰,影响AS的发病性.

关键词:
H3K27甲基化 H3K27甲基化Th17差异化差异化方法结性脊柱炎是一种疾病.这是表观遗传学.

更多相关视频

Author Spotlight: Achieving High-Purity In Vitro Differentiation of Th17 Cells Using Cytokine Concentration Modulation07:46

Author Spotlight: Achieving High-Purity In Vitro Differentiation of Th17 Cells Using Cytokine Concentration Modulation

Published on: October 25, 2024

3.0K
Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets07:12

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets

Published on: April 16, 2015

52.1K

相关概念视频

T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
1.0K