在单一时期和整个生命周期中,与高胆固醇血症相关的成本
Stephanie Reitzinger1, Miriam Reiss2, Thomas Czypionka2,3
1Institute for Advanced Studies, Josefstädter Str. 39, 1080, Vienna, Austria. reitzinger@ihs.ac.at.
概括
高胆固醇血症显著影响公众健康,由于心血管疾病风险增加,导致大量的社会成本. 降低低密度脂蛋白胆固醇 (LDL-C) 水平可以减轻死亡和经济损失.
科学领域:
- 公共卫生 公共卫生
- 卫生经济学 卫生经济学
- 流行病学 流行病学
背景情况:
- 高胆固醇血症是动脉样硬化心血管疾病的主要危险因素,减少健康寿命.
- 胆固醇水平升高导致缺血性心脏病,中风和其他心血管疾病的显著发病率和死亡率.
研究的目的:
- 量化奥地利高胆固醇血症所造成的综合社会成本.
- 分析高胆固醇血症对直接医疗,非医疗和间接经济成本的影响.
主要方法:
- 利用了有关胆固醇分布和心血管疾病相对风险的流行病学数据.
- 应用了可以归因于人口的分数来估计直接和间接类别的成本.
- 进行了生命周期分析,以预测2019年人口的未来患病和死亡成本.
主要成果:
- 大约50%的奥地利人口表现出高低密度脂蛋白胆固醇 (LDL-C) 水平,超过目标建议.
- 高胆固醇血症与8.2%的死亡有关,在生命周期的角度来看,总社会成本估计为8.06亿欧元 (占GDP的0.33%).
- 医疗费用达到3.121亿欧元,由于这种情况造成的生产损失约为4.94亿欧元.
结论:
- 很大一部分死亡,残疾养老金和劳动力市场损失都归因于高胆固醇血症.
- 减少人口的LDL-C水平为避免医疗保健支出和经济生产力损失提供了巨大的机会.
- 旨在降低胆固醇的干预措施可以为公众健康和奥地利经济带来相当大的好处.
相关概念视频
01:18Lipids: Dietary Sources and Requirements
731
Lipids are an essential component of a balanced human diet. Triglycerides, which make up the majority of dietary lipids, are found in both saturated fats—commonly present in meat, dairy products, and certain tropical plants like coconut, and hydrogenated oils such as margarine and baking shortenings (trans fats)—and unsaturated fats, which are abundant in seeds, nuts, olive oil, and most vegetable oils. The main sources of cholesterol include egg yolks, various meats and organ...
731
01:20Lipid-Lowering Drugs: Statins and Miscellaneous Agents
659
Hyperlipidemia, a medical condition often referred to as high cholesterol, is characterized by abnormally elevated levels of lipids in the bloodstream. When present in excess, these lipids, specifically cholesterol and triglycerides, can lead to serious health complications, often involving cardiovascular diseases. Illnesses like atherosclerosis, heart attacks, and pancreatitis have all been linked to untreated hyperlipidemia. This means controlling and regulating cholesterol and triglyceride...
659
01:29Cholesterol: Significance and Regulation
543
Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
Considering cholesterol and...
543
01:25Blood Studies for Cardiovascular System III: Serum Lipid Profile
156
Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
156
00:51Energy Budgets
9.2K
Organisms must balance energy intake with the energy required for growth, maintenance and reproduction. These trade-offs result in a variety of survivorship and reproductive strategies, including semelparity and iteroparity. Semelparous species, like annual plants, have only one reproductive episode in their lifetimes and consequently have short lifespans. Iteroparous species, by contrast, have many reproductive events during their lifetimes but have relatively few offspring. These two...
9.2K
01:31Lipid-derived Compounds in the Human Body
4.4K
Fats and lipids are crucial components in the human body. Some lipid-derived compounds, such as fat-soluble vitamins, eicosanoids, lipoproteins, and glycolipids, also play unique roles to support various biological processes .
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin,...
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin,...
4.4K