对手术前凝血功能变化和深静脉血栓发生率的评估,针对患有骨骨折的老年患者
1Trauma Department of Orthopedics, The Affiliated Hospital of Chengde Medical University, Chengde, China.
Clinical hemorheology and microcirculation
|March 22, 2024
概括
老年关节骨折患者的关节骨折 (FIF) 显示出较高的深静脉血栓形成 (DVT) 风险和高凝血能力,而不是那些关节部骨折 (FNF). 增加的D-二聚合物和FDP水平表明风险更高.
科学领域:
- 老年医学 老年医学
- 血管外科 血管外科
- 血液学 血液学 血液学
背景情况:
- 骨折在老年人中很常见,增加了深静脉血栓症 (DVT) 的风险.
- 在部骨折患者的手术前DVT可能会导致严重的并发症.
- 了解基于骨折类型的DVT发生率和凝血变化对于预防至关重要.
研究的目的:
- 分析患有骨骨折的老年患者手术前深静脉血栓 (DVT) 发生率.
- 为了研究与骨折位置相关的凝血功能的变化 (股骨间胸口与股骨部).
- 在这个脆弱人群中提供预防和管理手术前DVT的指导.
主要方法:
- 282名患有关节骨折的老年患者被分为大腿间骨折 (FIF) 和大腿部骨折 (FNF) 组.
- 基线特征,手术前DVT发生率和七个凝血参数进行了比较.
- 评估了血小板计数和D-二元和纤维素/纤维素降解产物 (FDP) 的水平.
主要成果:
- 在FIF和FNF组之间没有发现基线特征的显著差异.
- 与FNF组相比,FIF组的手术前DVT发生率明显高于FNF组.
- 患有FIF的患者表现出显著更高的D-二聚体和FDPs水平,表明高凝固性.
结论:
- 患有大腿骨间骨折的老年患者在手术前出现较高的DVT和高凝血率.
- 升高的D-二聚体和FDP水平与FIF患者的DVT风险增加有关.
- 临床医生应对老年FIF患者的DVT保持警,特别是那些D-二次数和FDPs升高的患者.
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