应强调确定和报告研究重点,以增加研究价值:经验分析
Yicheng Gao1,2,3, Zhihan Liu1,2,3, Rui Cao1,2,3
1Centre for Evidence-Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
PloS one
|March 22, 2024
概括
中国临床实践指南 (CPG) 需要在报告研究重点方面进行改进,特别是PICO元素. 与中国CPG相比,GRADE CPG更好地报告了比较有效性和干预效率.
科学领域:
- 健康研究方法 卫生研究方法
- 临床实践指南 临床实践指南
- 基于证据的医学基于证据的医学.
背景情况:
- 研究重点对于指导未来的健康研究至关重要.
- 建议评级,开发和评估 (GRADE) 工作组为准则制定提供了一个框架.
- 中国临床实践指南 (CPG) 在医疗保健中越来越多.
研究的目的:
- 为了比较GRADE CPG和中国CPG的研究重点的呈现和报告.
- 确定在中国CPG的研究重点发展方面需要改进的领域.
主要方法:
- 进行了一项方法论性的经验分析.
- 搜索了多个数据库,包括PubMed,Embase和中国数据库.
- 包括 45 个 GRADE CPG 和 90 个在 2018-2022 年间出版的中国 CPG.
- 独立审查员对研究重点进行了选并提取了数据.
主要成果:
- 在GRADE和中国CPG中,超过70%的研究重点都具有人口和干预 (PI) 结构.
- 与中国CPG (2.9%) 相比,GRADE CPG更频繁地报告了人口,干预,比较和结果 (PICO) 结构 (14.8%).
- 与中国的CPG相比,GRADE CPG显示了比较有效性研究重点的报告量大约是中国CPG的两倍.
结论:
- 在开发和报告中国CPG的研究优先事项方面需要显著改进.
- 在中国的CPG中,关键的PICO元素呈现不充分,对价值观,偏好,健康公平和可行性更不重视.
- 加强在确定和报告研究重点方面的努力对于未来的指导方针制定至关重要.
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