创伤性脑损伤后疲劳和认知障碍的发生率
Traver J Wright1, Timothy R Elliott2, Kathleen M Randolph1
1Department of Internal Medicine, The University of Texas Medical Branch, Galveston, Texas, United States of America.
PloS one
|March 22, 2024
概括
有创伤性脑损伤 (TBI) 病史的人报告疲劳和认知障碍显著增加. 这些症状随着TBI严重程度的增加而恶化,即使在轻微伤害后也是如此.
科学领域:
- 神经科学是一个神经科学.
- 临床心理学 临床心理学
背景情况:
- 创伤性脑损伤 (TBI) 可以导致持续的疲劳和认知问题.
- 在TBI患者中自我报告的认知障碍通常会被标准的神经认知测试遗漏.
- 在TBI幸存者中评估这些并发症症状的患病率和严重程度至关重要.
研究的目的:
- 为了确定患有TBI病史的个体中疲劳和认知障碍的患病率.
- 调查TBI严重程度和报告的症状之间的关系.
- 为了比较TBI患者的症状水平与没有TBI史的对照组.
主要方法:
- 利用数字疲劳和改变认知量表 (FACs) 调查问卷进行自我报告的症状评估.
- 在线招募519名成年人 (18-70岁),收集人口统计和TBI历史数据.
- 包括204名有TBI史的参与者和315名没有TBI史的参与者.
主要成果:
- 与非TBI组 (39.5 ± 23.9) 相比,TBI组在FAC (57.7 ± 22.2) 上得分明显高,这表明疲劳和认知障碍更大.
- 在所有TBI严重程度中观察到FACs得分升高:轻度 (53.9 ± 21.9),中度 (54.8 ± 24.4) 和严重 (59.7 ± 20.9).
- 在TBI严重程度和症状严重程度之间发现了显著的正相关性 (p<0.0001,r = 0.3165).
结论:
- 患有TBI病史的成年人,包括轻度病例,报告的疲劳和认知障碍明显高于没有TBI的成年人.
- 报告的疲劳和认知障碍的严重程度与TBI的严重程度成比例增加.
- 初步研究结果表明,无论TBI病史如何,在以前感染COVID-19的人群中,FAC得分可能会升高,这与TBI病史无关.
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