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对新生儿深静脉导管相关的血液感染的分析和危险因素

Yan Zhang¹, Shufang Li, Yanmin Li

¹Department of Neonatology, First Hospital of Handan City, Hebei Province, China.

|March 22, 2024

概括

在接受外围插入中央静脉导管 (PICC) 的新生儿中,与导管相关的血液感染发生率为4.74%. 过早分娩,低出生体重和漫长的导管时间是关键的危险因素.

科学领域:

新生儿重症监护室新生儿重症监护室
传染性疾病传染性疾病
与医疗器械相关的感染

背景情况:

周围插入的中央导管 (PICC) 在新生儿护理中至关重要.
导管相关的血流感染 (CRBSI) 对新生儿构成重大风险.
了解CRBSI发病率和风险因素对于预防至关重要.

研究的目的:

确定新生儿PICC相关血流感染的发病率和病原特征.
在这个人群中识别与CRBSI相关的风险因素.
为减少PICC相关感染率的战略提供信息.

主要方法:

对接受PICCs的680名新生儿的临床数据进行了回顾性分析.
单变量和多变量分析以确定CRBSI的风险因素.
病原体的识别和表征.

主要成果:

总体的CRBSI率为4.74% (38/680名新生儿).
独立的风险因素包括早产,低出生体重,肠道营养,长时间的导管治疗和低的5分钟APGAR分数.
常见的病原体包括真菌 (例如,Candida parapsilosis),克拉姆阳性细菌 (例如,凝结酶阴性葡萄球菌) 和克拉姆阴性细菌 (例如,Klebsiella pneumoniae,大肠杆菌).

结论:

低出生体重,早产,肠外营养,延长导管停留时间和低的5分钟APGAR分数是PICCs新生儿CRBSI的重要独立风险因素.
菌和多药耐药细菌是值得注意的病原体.
研究结果强调需要针对高风险新生儿采取有针对性的预防措施.

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