胆固醇补充剂和饥饿和腹感知:随机对照试验的系统审查和剂量反应元分析
Negin Nikrad1, Mehdi Ghaffari Sarghein1, Mahdieh Abbasalizad Farhangi2
1Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Nutrition reviews
|March 22, 2024
概括
提拉科因补充剂有效地减少饥饿感并增加腹感,特别是在更短的干预时间内. 需要进一步的研究才能充分理解这种食欲调节关系.
科学领域:
- 营养科学 营养科学
- 食补充剂的使用
- 调节食欲 调节食欲是什么意思
背景情况:
- 提拉科因补充剂已被提议影响食欲,但现有的研究存在矛盾.
- 之前的研究表明对食欲控制有潜在的益处,需要进一步研究.
研究的目的:
- 系统地审查和分析甲基补充剂对饥饿和腹变化的疗效.
- 巩固目前关于甲状腺素对食欲感知影响的证据.
主要方法:
- 在PubMed,Scopus和Web of Science数据库中进行了全面的文献搜索,截至2023年5月.
- 选择并分析了使用视觉模拟秤 (VAS) 测量食欲的五项相关研究.
- 数据提取包括研究设计,参与者细节,干预具体情况和发现;研究质量使用Jadad尺度进行评估.
主要成果:
- 分析显示,补充甲基可显著降低饥饿感 (WMD: -2.415 mm; P < 0.001) 并增加腹感 (WMD: +4.602 mm; P < 0.001).
- 在56天以下的干预期内,在每天5g和每天7.4g的剂量下观察到最佳的饥饿减轻.
- 在84天以下的干预和更高的基线度 (VAS>45毫米) 时,观察到增加了度感知.
结论:
- 提拉科因补充剂在减少饥饿和增强腹感方面表现出良好的效果,特别是在干预时间较短的情况下.
- 这些发现突显了thylakoids在食欲控制中的潜力.
- 建议进行进一步的临床试验,以阐明精确的机制和长期影响.
相关概念视频
01:30Regulation of Food Intake
228
Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
228
01:25Primary Motives: Hunger and Thirst
190
Hunger and thirst are fundamental physiological drives crucial for maintaining homeostasis and ensuring the survival of both humans and animals. These drives are regulated through complex interactions between the brain, hormones, and sensory receptors.
Hunger arises when the brain detects changes in the body's nutrient levels, including glucose, lipids, amino acids, and hormones such as ghrelin and leptin. The hypothalamus plays a central role in hunger regulation. The lateral hypothalamus...
Hunger arises when the brain detects changes in the body's nutrient levels, including glucose, lipids, amino acids, and hormones such as ghrelin and leptin. The hypothalamus plays a central role in hunger regulation. The lateral hypothalamus...
190
01:24Metabolic States of the Body: Fasting and Starvation
1.4K
During the initial hours of fasting, the body uses up its glycogen stores as an energy source. Once these glycogen reserves are depleted, the body begins breaking down stored triglycerides and structural proteins. During this stage, glycerol becomes a key substrate for gluconeogenesis, while free fatty acids undergo beta-oxidation to provide energy for tissues, such as skeletal muscle. In the fasting state, the body spares protein breakdown as much as possible to conserve muscle and structural...
1.4K